For a family strip with bite, you can't do better than The Grizzwells, starring a four-bear family of grizzlies.
Saturday Morning Breakfast Cereal (SMBC) is a daily gag comic about science, love, sex, religion, philosophy, economics, and other topics probably best left to people who know what they're talking about.
Saturday Morning Breakfast Cereal
SPECIAL NOTE: As of August 26, 2015, Basic Instructions is now in reruns. See the final comic here. Follow from the start here. Basic Instructions started out as a small side feature Scott Meyer created to entertain people who came to his website looking to hire a comedian. It wasn't long before the comic was far more popular than anything Scott ever did as a comedian.Basic Instructions is a series of guides meant to help you lead a better life. They cover topics as diverse as "How to Deal with Boredom" and "How to Travel Back in Time to Deliver a Dire Warning to Your Former Self". Basic Instructions is populated with exaggerated versions of Scott, his family and his friends, which has caused no small amount of unpleasantness.
The most beloved comic strip in history is an American cultural icon.
WuMo celebrates life's absurdity, holding up a fun-house mirror to our modern world and everyone who lives in it. Populated by crazy beavers, disgruntled office workers, feuding couples, gangster rappers and pool-playing unicorns, WuMo has grown from an underground sensation to an instant classic.
Wulff & Morgenthaler
Moderately Confused offers a gently absurd and playfully witty take on the vagaries of daily life, technology and politics.
Most children would be terrified by monsters under the bed, rogue cyborgs, destructive aliens and dicey nuclear experiments. But Lio is not your average kid. Mark Tatulli renders this pantomime strip in a pen-and-ink style that matches the strips' dark humor and imaginative spirit.
F Minus is short on life lessons, precious moments, and pearls of wisdom. Instead, this absurdist single panel comic tackles life's serious issues, pins them to the ground and steals their lunch money. Then it feels a little bit guilty and gives some of it back.
Nancy was created in the 1930s by Ernie Bushmiller. Since 1995, the strip has been drawn and written by Guy Gilchrist. Nancy is famed for its gentle humor and playful sight gags. Nancy remains a devoted friend to her pal Sluggo, her Aunt Fritzi, and many others. Her childlike innocence never wavers.
Dinosaur Comics is a comic where the pictures never change, but the words do! IT'S HONESTLY BETTER THAN IT SOUNDS. T-Rex, Utahraptor, Dromiceiomimus and friends discuss Very Important Things, ranging from the nature of love all the way to whether or not who smelt it is truly the same as whosoever dealt it. (This hasn't actually happened in the comic, but it's actually not a bad idea).