We ad a cat that would not eat pills, even mixed with food. We would have to give it to him directly. He was almost 30 pounds. I would hold him down and my husband would force the pill into his mouth. One time, after a particularly brutal battle, we SAW his throat working, swallowing, so I let him go. He took a few steps, then PTOOIE he spit the pill out! After that, we always ordered liquid.