From the song Sweet Betsy of Pike: “Out on the prairie one bright starry night/They broke out the whiskey and Betsy got tight./She sang and she shouted, she danced o’er the plain/And showed her bare arse to the whole wagon train.”
In the Universal series of movies, the Monster (played by Boris Karloff in three movies, then by other actors) IS named Frankenstein after his creator. The character Byron in the prologue of Bride of Frankenstein refers to the Monster as Frankenstein. This comic strip is spoofing the Karloff model, so the Monster is named Frankenstein in that context.
A similar conflict is in the backstory of Jack Reacher, hero of a series of detective books.