Calvin and Hobbes by Bill Watterson for December 02, 1992
Calvin: Do you hate being a girl? Susie: It's gotta be better than the alternative. Calvin: What's it like? Is it like being a bug? Susie: Like a what?! Calvin: I imagine bugs and girls have a dim perception that nature played a cruel trick on them, but they lack the intelligence to really comprehend the magnitude of it. I must've put my finger on it.