Doonesbury by Garry Trudeau for December 24, 1974
Zonker: Dad! Mom! Signs of life from Uncle Duke! Man: A breakthrough, son?! Zonker: Could be! C'mon, Uncle Duke - you can do it! Shake it off, man, shake it off! Man + Woman: C'mon, Duke! Hang in there, man! Zonker: I can see his pupils! Yes... yes... he's got it! That's it! He's conscious! Man + Woman: Yea!! Zonker: Merry Christmas, Uncle Duke! Duke: Oh, wow! A giant lizard!