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The innocent and naïve pig protagonist, Ham Shears, moves to the big city to try and make something of himself and mistakenly ends up working at a butcher shop. The well-meaning Ham doesn't make the connection between animals and meat products while the titular and eccentric "Boss" of "Boss's Butcher Shop" doesn't seem to notice the implications of hiring a pig to work for him.
Uncomfortable encounters with butcher shop customers ensue and eventually Ham Shears meets two girls from the neighborhood, the plucky Jill and no-nonsense Ingrid. They end up befriending Ham Shears and get wrapped up in the day-to-day weirdness that comes from knowing an anthropomorphic pig.